Active substance: Orlistat
Brown urine How does Alli work? Lipase, an enzyme found in the digestive tract, helps break down dietary fat into smaller components, so it can be used or stored for energy. Orlistat inhibits the work of lipase.
When you take the drug with a meal, about 25 percent of the fat you consume isn't broken down and is eliminated through bowel movements.
How much weight could I lose using Alli? More than 40 percent of people taking Alli while following a calorie-restricted diet and increasing physical activity lost 5 percent or more of their body weight within a year.
Clinically meaningful weight loss — enough weight loss to begin lowering the risk of cardiovascular disease, diabetes and other diseases — is generally defined as 5 percent or more of body weight. People who ate a calorie-restricted diet, exercised regularly and took Alli lost an average of 5.
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How is Alli taken? One 60-milligram Alli pill is taken within an hour of a fat-containing meal up to three times a day.
Daily fat intake should be distributed over the three main meals and should be no more than 30 percent of total calories. The manufacturer recommends a fat intake of about 15 grams a meal. If you eat a meal that contains no fat, then you don't need a dose of Alli.
If you take Alli with a high-fat meal, you will likely experience more-severe gastrointestinal side effects. Alli can reduce the absorption of fat-soluble nutrients, including beta carotene and vitamins A, E and K.