Active substance: Norfloxacin
Careful monitoring and supportive treatment, monitoring of renal and liver function, and maintaining adequate hydration is recommended by the manufacturer.
At the respective doses, mean peak serum and plasma concentrations of 0. The effective half-life of norfloxacin in serum and plasma is 3—4 hours. Steady-state concentrations of norfloxacin will be attained within two days of dosing. Norfloxacin is least soluble at urinary pH of 7.
Other companies initiated fluoroquinolone discovery programs in the aftermath of the publication of the norfloxacin patent.
Bayer Pharmaceuticals discovered that the addition of a single carbon atom to the norfloxacin structure provided another 4 to 10-fold improvement in activity.
In the treatment of urinary tract infections, adults will generally need to use this medicine for 7-10 days. In chronic inflammation of the prostate the usual duration of treatment is 4 weeks. The symptoms of urinary tract infection, such as a burning sensation experienced during passing water, pain, and fever, will generally disappear within 1-2 days.
However, the treatment course with this medicine should be continued for up to 12 weeks in chronic relapsing urinary tract infections.
If you take more Norfloxacin 400 mg than you should If you have taken a double dose, you only need to contact your doctor if side effects occur.
Continue taking your medicine regularly as prescribed. If you have taken more than a double dose by mistake, contact your doctor immediately.
If you forget to take Norfloxacin 400 mg Do not take a double dose to make up for a forgotten tablet, just carry on with the next one as normal. If you stop taking Norfloxacin 400 mg It is important that you complete the course of treatment, even if you begin to feel better after a few days.
If you have any further questions on the use of this product, ask your doctor or pharmacist or nurse.
Like all medicines, this medicine can cause side effects, although not everybody gets them. Allergic reactions can, very rarely, be life-threatening.
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For these reasons, before you start taking norfloxacin it is important that your doctor knows: If you are pregnant, trying for a baby, or breast-feeding.
If you are under 18 years of age. If you have ever experienced a problem with your tendons after taking another quinolone antibiotic these are called ofloxacin, levofloxacin, ciprofloxacin, moxifloxacin, and nalidixic acid. If you have any problems with the way your kidneys work.