Active substance: Clomiphene
Typically it causes 2 or 3 eggs to ovulate. This improves pregnancy rates, but also increases the likelihood of multiple gestation twins or triplets.
The risk of multiple gestation when taking Clomid is still generally low. What are the risks of multiple gestation? An ultrasound performed before ovulation can tell you how many eggs you are likely to ovulate and can estimate the risk for multiple gestation.
At that time, we will either stimulate you with a lower dose of Clomid or try another medication in order to lessen the risk of a multiple gestation.
Sperm motility also significantly increased, but there was no significant increase in normal morphology.The Use of Clomid for Male Infertility We can use Clomid for male infertility Once the urologist has eliminated an anatomic cause for the problem, we can treat men with clomiphene citrate Clomid.
We were most pleased by the fact that, although each of these infertile couples was planning on doing IVF due to significant male factor, 58. This study received significant notoriety when we presented these results at the annual meeting of the American Society for Reproductive Medicine ASRM, and several other investigators have subsequently found the same results that we reported.
Clomid for men is used when a low sperm count is caused by low testosterone levels In some men, a low sperm count is caused by a low testosterone level.
It might seem logical to give more testosterone to a man with a low testosterone level; however, doing so can actually decrease his sperm count.
A similar situation exists in women, as birth control pills with estrogen prevent egg development and ovulation. A 1999 clinical study at Texas Fertility Center found that Clomid caused a statistically significant increase in sperm concentration.
Multiple studies have shown that women who have the same indications as for ovulation induction with clomid can also use letrozole as an alternative.
A few head to head trials of clomiphene citrate and letrozole have shown similar results so far. Women who have side effects with clomiphene citrate can consider letrozole as an alternative. It is taken for 5 days early in the cycle.
The starting dose is 2. If ovulation does not occur the dose can be raised 2.
Most practitioners do not exceed 7. Gonadotropins The gonadotropins, also called Repronex, Bravelle, Menopur, Gonal F, or Follistim are injectable fertility medications that can be used for ovulation induction.
After approximately two weeks, the pituitary releases a surge of LH hormone, triggering ovulation.
At this stage, the follicle, now known as the corpus luteum, begins to produce the hormone progesterone, which serves to thicken the uterine lining to prepare for possible pregnancy. Two weeks after ovulation, if a pregnancy has not occurred, the corpus luteum stops progesterone production, the endometrium sloughs off and menstrual bleeding occurs.
Ovulation-Inducing Fertility Drugs Any number of conditions can hamper the body's ability to ovulate effectively.
One of the primary ways to address this challenge is with medications that stimulate the ovarian follicles to produce multiple eggs in one cycle. Clomiphene is a synthetic chemical, taken orally, that binds to estrogen receptors in the brain and causes pituitary FSH levels to rise see below.
Gonadotropins are identical to human protein hormones FSH and LH and, given by injection, bypass the pituitary gland and directly stimulate the ovaries.
Clomiphene Citrate treatment Clomiphene is a long trusted oral medication relied upon for its safety, effectiveness and relatively low cost.
Clomiphene is used to treat absent or irregular menstrual cycles ovulation induction, to address a condition called luteal phase defect by increasing progesterone secretion during the second half of the cycle and to make menstrual cycle lengths more predictable, thus improving the timing of intercourse or artificial insemination.