Active substance: Isotretinoin
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Prevalence of facial acne vulgaris in late adolescence and in adults. Br Med J. Oral isotretinoin is as effective as a combination of oral isotretinoin and topical anti-acne agents in nodulocystic acne.
Indian J Dermatol Venereol Leprol.
Roaccutane treatment guidelines: Results of an international survey. Isotretinoin versus placebo in the treatment of cystic acne.
A randomized double-blind study. J Am Acad Dermatol. A review of the European Directive for prescribing systemic isotretinoin for acne vulgaris.
J Eur Acad Dermatol Venereol. Isotretinoin therapy for acne: Results of a multicenter dose-response study.
Brelsford M, Beute TC. Preventing and managing the side effects of isotretinoin.
Semin Cutan Med Surg. Association of suicide attempts with acne and treatment with isotretinoin: Retrospective Swedish cohort study. Important Do not take isotretinoin capsules if you think you're pregnant, you know you're pregnant, or if you're breastfeeding.
Men and isotretinoin capsules Men can safely take isotretinoin capsules if they and their partner are trying for a baby, or their partner is pregnant.
Isotretinoin capsules don't seem to damage sperm. Only tiny amounts of isotretinoin get into semen, which is too little to harm the unborn baby. Cautions with other medicines Some medicines and isotretinoin capsules can interfere with each other, and make it more likely that you'll have side effects.
Important Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.
Common questions How do isotretinoin capsules work? Isotretinoin capsules are only for severe acne.